Embedded Motion for Next Generation Sequencing and Diagnostics
Enabling Photonics for Higher Performing DNA Sequencing and Diagnostics
As Polymerase chain reaction (PCR) and diagnostic instruments move closer to the point of care, miniaturization becomes critical, and optical light paths become more challenging. New Scale Technologies works with life science and photonics companies to overcome these barriers. Our miniaturized motion modules for NGS and diagnostic instruments enable engineers to:
- Optimize light sources – advanced beam shaping and laser beam focusing
- Improve sensing and detection – high-precision camera focus modules
- Miniaturize optomechanical systems – embedded motion control technology reduces system size while maintaining performance
New Scale Technologies’ smart motion control modules are designed and manufactured in the US, offering customizable modules that minimize system costs and expedite time to market.
Miniaturizing Photonics with Motion Control for High-Throughput NGS and Portable Diagnostics
Embedded Motion for NGS Instruments
In the race to develop next-gen DNA sequencing instruments, NST speeds commercialization by simplifying optomechanical systems, improving light quality and enabling multi-channel density for faster data collection.
Learn how we’ve helped market leaders in NGS improve throughput and lower costs.
Order of Magnitude Miniaturization for Desktop HiFi System
NST helped this DNA sequencing market leader shrink their system to 1/10 its original volume, creating a desktop solution accessible for in-office screening, even in underserved regions. How was this achieved?
- Embedded Controller: Eliminated the need for bulky external electronics.
- Compact Design: Miniaturization allowed more channels in a smaller footprint.
Enabling Backpack Portable Diagnostics
NST has designed and deployed thousands of motion control modules for backpack HIV testing systems, enabling early detection with faster, more reliable data collection.
How did we achieve this?
- Rugged Design: Fewer cables for durability in the field.
- Precision Targeting: Lightweight 4-DOF alignment improves laser accuracy and data quality.
- Enhanced Signal-to-Noise: Faster, more reliable results.
Workflow of DNA Sequencing Systems: Typical System vs. Smart Motion Control
Smart Motion Control in NGS:
- Laser beam quality
- Laser beam steering
- Exposure control
- Signal detection
- Camera focus
Proven, Reliable Expertise
New Scale Technologies has provided micro-mechatronic systems to market leaders in sequencing and diagnostics, with decades of performance in the field. Made in Victor, NY, New Scale has the capacity to design and manufacture for programs demanding volume.
Based on our proprietary SQUIGGLE™ technology, New Scale provides standard modules and custom engineering of motors and micro motion systems.
M3 Focus Module
Incorporate a piezoelectric SQUIGGLE micro motor, built-in controller, position sensors and microprocessor on one tiny package.
Input 3.3VDC and simple high-level commands from your system processor. No external control board needed.
For the smallest embedded optical systems in handheld and portable instruments, M3-F and M3-FS offer:
- Superior image quality
- Simple system integration
- Flexible, production-ready system
- Lowest cost, fastest time to market
Linear Micro Stage
Unlock Ultra-Precise Motion Control with M3-LS Linear Micro Stages
Engineered for high-resolution positioning in tight spaces, the M3-LS Linear Micro Stage delivers 0.5 µm resolution, absolute encoding, and high lateral stability—making it ideal for applications in microscopy, biomedical devices, photonics, and UAV systems.
Whether you’re steering optics, sensors, or probes, M3-LS stages offer:
- Compact footprint
- Plug-and-play integration
- Reliable performance
Rotary Stages
Achieve High-Resolution Angular Positioning with M3-RS Rotary Smart Stages
The M3-RS Rotary Stage is the smallest all-in-one rotary positioning solution on the market, measuring less than 12 x 22 x 16 mm including its embedded controller.
From beam steering in photonics to rotational alignment in surgical tools, M3-RS stages deliver unmatched precision and reliability. Their compact design supports:
- Low SWaP (Size, Weight, and Power)
- Fast integration
- Robust performance